BioGem Blog

Bioinformatics derives knowledge from computer analysis of biological data. These can consist of the information stored in the genetic code, but also experimental results from various sources, patient statistics, and scientific literature. Research in bioinformatics includes method development for storage, retrieval, and analysis of the data. Bioinformatics is a rapidly developing branch of biology and is highly interdisciplinary, using techniques and concepts from informatics, statistics, mathematics, chemistry, biochemistry, physics, and linguistics. It has many practical applications in different areas of biology and medicine. Roughly, bioinformatics describes any use of computers to handle biological information. In practice the definition used by most people is narrower; bioinformatics to them is a synonym for "computational molecular biology" – the use of computers to characterize the molecular components of living things. Simple definition for Bioinformatics:- “ T...

In bioinformatics/computational biology, a sequence is represented by ordered succession of characters (1-letter code of DNA/RNA/amino acid) known as alphabets. The standard type of alphabets include DNA alphabet [A, T, C, G], RNA alphabet [A, U, C, G], and amino acid alphabet [A, C, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, Y]. While, non-standard alphabets include DNA/RNA alphabet [B, D, H, K, M, N, R, S, V, W, Y], and amino acid alphabet [B, J, O, U , X, Z]. List of standard and non-standard DNA/RNA alphabets with 1-letter code is given in table below. Nucleotide 1-letter code Adenine A C, G, T B Cytosine C A, G, T D Guanine G A, C, T H G, T K A, C M A, T, U, C, G N A, G R G, C S Thymine T Uracil U A, C, G V A, T W C, T Y List of standard and non-standard amino-acid alphabets with 3-letter code...